Skip to main content
Call or Text: (914) 546-6571 Refer a Patient (for providers)

Ketamine IV infusion has been shown to reduce cravings for alcohol, cocaine, and opiates.

Clinical studies support ketamine's ability to reduce both the frequency and intensity of substance cravings. At PMC Psychedelic, we offer this as an adjunct treatment for patients managing addiction alongside broader care.

This is an adjunct treatment — not a standalone addiction program.

PMC Psychedelic is not an addiction treatment center or detox facility. Ketamine IV infusion is used here as a clinically supported adjunct to reduce cravings — meaning it works alongside, not instead of, addiction treatment, recovery programs, and ongoing therapeutic support.
Patients considering this treatment should be working with an addiction specialist, counselor, or support program. Dr. Rueda coordinates with your existing care team with your consent.

What ketamine actually does for substance cravings.

Substance cravings are maintained by deeply conditioned neural pathways — circuits that link environmental cues, emotional states, and memory to the urge to use. These pathways are notoriously resistant to standard treatments.
Ketamine IV infusion triggers rapid neuroplastic changes through the glutamate system. Clinical studies suggest this can meaningfully disrupt craving pathways — reducing both how often cravings occur and how intensely they are felt. The effect is not a cure, but for many patients it creates a window of reduced craving intensity during which other recovery work becomes more effective.

The three substances with the strongest clinical evidence:

Alcohol

Clinical studies show ketamine meaningfully reduces both the frequency and intensity of alcohol cravings.

Cocaine

Research supports ketamine in reducing cocaine craving episodes and the urge intensity that drives relapse.

Opiates (including Fentanyl)

Opiate cravings — including fentanyl dependence — have been studied with ketamine, with results showing reduced craving frequency and severity.
The evidence for these three is the most established. Other substances may also benefit, but PMC only makes clinical claims supported by published research.

How we administer ketamine for craving reduction.

Adjunct Craving Reduction Treatment · Out-of-Pocket

Ketamine IV Infusion

  • Standard induction: 6 infusions over 2 to 3 weeks.
  • Each session approximately 1 to 2 hours including monitoring time.
  • Precise IV dosing controlled by our clinical team throughout.
  • You cannot drive home after a session — please arrange a ride.
  • Paid out of pocket — no insurance required, no prior authorization.
  • Works best when used alongside an active addiction recovery program.
Many patients who come to us for craving reduction also have co-occurring depression or PTSD. Ketamine addresses all of these simultaneously — Dr. Rueda will discuss your full picture during your consultation.

Who is a good candidate for this treatment.

Ketamine IV infusion for craving reduction is appropriate for adults who:
  • Are managing alcohol, cocaine, or opiate dependence as part of a broader recovery plan.
  • Have persistent cravings that are making sobriety or reduced use significantly harder.
  • Are working with an addiction counselor, recovery program, or support network.
  • Are medically stable and appropriate for outpatient care.
  • Can attend a series of infusion sessions and arrange transportation home.
This is not a substitute for addiction treatment. Patients must be actively engaged in or willing to engage in a broader recovery framework to benefit most from this adjunct approach.

Common questions.

Not in the traditional sense. PMC uses ketamine IV infusion specifically to reduce the frequency and intensity of cravings — not as a primary addiction treatment. It works best as an adjunct alongside an active recovery program, counseling, or support network. Dr. Rueda will discuss this framing clearly during your consultation.

Ketamine does carry a potential for misuse at recreational doses. In a clinical setting, it is administered at subanesthetic doses under direct medical supervision — a context that is fundamentally different from recreational use. Dr. Rueda evaluates each patient's history, including substance use history, before recommending treatment.

Ketamine IV infusion is paid out of pocket. It is not covered by insurance for substance use indications. If you have co-occurring depression, Spravato may be covered by your PPO plan. We verify coverage before your first appointment.

Some patients report a meaningful reduction in craving intensity within 24 to 48 hours of early sessions. Individual response varies. The goal is not elimination of cravings but a meaningful reduction that makes recovery work more manageable.

Get Started

Looking for additional support in your recovery?

Request a consult with Dr. Rueda's team. We will review your history, understand your current recovery situation, and discuss whether ketamine infusion is an appropriate adjunct for you.
PMC Psychedelic · Port Chester, NY · Serving Westchester & Fairfield County
© 2026 PMC Psychedelic Medicine Centers of America. All rights reserved.