- Fast relief options for treatment-resistant depression.
- Ketamine infusion for depression promotes rapid symptom reduction.
- FDA-approved Spravato depression treatment available at PMC Heal.
- Personalized care plans for safe, effective depression therapies.
For people living with depression, there’s nothing more disheartening than doing everything “right” and still feeling stuck. You’ve tried the antidepressants. You’ve gone to therapy. You’ve adjusted your diet, exercise, and sleep. And yet, the fog won’t lift.
This is the reality of treatment-resistant depression—a condition that affects millions of people who find little or no relief from standard interventions. If that sounds familiar, it’s not the end of the road. Innovative therapies like ketamine treatment for depression are offering new hope, and for many, fast relief.
At PMC Heal, we specialize in next-generation psychiatric care that includes both ketamine infusion for depression and Spravato depression treatment. These are not just experimental ideas—they’re science-backed treatments, with real results, for people who’ve felt like nothing works.
What Is Ketamine and How Does It Work?
Originally developed as an anesthetic, ketamine has long been known in the medical world for its powerful effects on the brain. But in the last decade, researchers have uncovered something remarkable: at lower, controlled doses, ketamine can significantly reduce symptoms of depression, often within hours.
So how does it work? Unlike SSRIs and other conventional antidepressants that act on serotonin and take weeks to build up, ketamine works on the glutamate system—a key neurotransmitter involved in learning, memory, and mood. This interaction helps spark neuroplasticity, encouraging the brain to form new connections and “reset” dysfunctional patterns.
Patients receiving ketamine infusion for depression often describe it as a lifting of the weight they’ve been carrying—sometimes within a single session. While it’s not a magic cure, it offers rapid symptom relief in ways traditional antidepressants can’t, especially for those facing intense or long-term depression.
What to Expect from Ketamine Therapy at PMC Heal
Starting something new, especially when you’ve already tried so much, can be intimidating. At PMC Heal, we make the process welcoming, informed, and centered around you.
It begins with a personalized consultation. We’ll review your mental health history, current symptoms, and previous treatments to determine if ketamine treatment for depression is the right fit. From there, eligible patients begin a supervised treatment plan that typically includes several infusions spaced over a few weeks.
Each session is conducted in a calm, clinical setting. You’ll be monitored throughout the infusion to ensure safety and comfort. The dissociative effects of ketamine usually wear off within an hour or two after treatment, and our care team is with you every step of the way.
We pride ourselves on upholding the highest clinical standards while offering compassionate, non-judgmental support. This isn’t just about administering medication—it’s about giving patients a new chance at healing with dignity and care.
What Is Spravato and How Is It Different from Ketamine?
You may have also heard of Spravato—and you’re not alone in wondering how it compares. Spravato depression treatment uses esketamine, a chemical variant of ketamine, delivered as a nasal spray. What sets it apart is its FDA approval specifically for treatment-resistant depression and major depressive disorder with suicidal thoughts.
Like ketamine infusions, Spravato acts quickly and targets the glutamate system. But because it’s FDA-approved, it’s often covered by insurance—a major advantage for many patients. Sessions are conducted in a clinic and require staying under observation for a few hours after each dose.
PMC Heal is proud to offer both Spravato and traditional ketamine therapies. Some patients may be better suited to one or the other based on medical history, insurance coverage, or personal preferences. We help you understand your options clearly, so you can make the best decision for your mental health.
